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Hypericumperforatum L. Showed Antinociceptive Effects Through Opioidergic And Serotonergic Systems

Figure 3: Pre-treatment with intrathecal injection of Methysergide(Methy) 30μg /rat on analgesia induced by intraperitoneal injection of 400mg/kg aqueous extract Hp on Tail flick test.(n=6). A. Predrug □ and post drug ■ latency were measured(by paired t-test). B.Maximum possible effect (MPE) inhibited by Methysergid (Methy) pretreatment (*p<0.5, un-paired t-test).

Pre-treatment with intrathecal injection of Methysergide(Methy) 30μg /rat on analgesia induced by intraperitoneal injection of 400mg/kg aqueous extract Hp on Tail flick test.(n=6). A. Predrug □ and post drug ■ latency were measured(by paired t-test). B.Maximum possible effect (MPE) inhibited by Methysergid (Methy) pretreatment (*p<0.5, un-paired t-test).
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