| Reference |
Healthcare issues that need to be addressed |
| (Kwon & Yoo, 2021; Kothari et al., 2021; Usman et al., 2021; Vervoort et al., 2020) |
Lack of research in the healthcare domain based on blockchain interoperability, interoperability implementation of different technologies |
| (Hasselgren et al., 2020; Kothari et al., 2021; Tandon et al., 2020) |
Data security, Data integrity |
| (Sharma & Balamurugan, 2020) |
User authentication |
| (Tariq et al., 2020) |
Blockchain combined with IoT in the drug supply chain |
| (De Aguiar et al., 2020)[ |
Data exchange structure |
| (Chukwu & Garg, 2020) |
Performance and cost |
| (Ellouze et al., 2020) |
Blockchain efficiently, big data of medical records |
| (Yaqoob et al., 2021) |
Blockchain immaturity, scalability, interoperability, stand-alone projects, difficult integration with existing healthcare systems, complexity |
| (Capece & Lorenzi, 2020) |
Privacy and scalability |
| (Durneva et al., 2020) |
How to implement decentralized organizations, applications, and services based on blockchain |